产品编号：GM-26840AB
产品名称：Anti-H_4-1BB hIgG2 Antibody(Utomilumab)
目录价：询价
产品编号：GM-26840AB
产品名称：Anti-H_4-1BB hIgG2 Antibody(Utomilumab)
目录价：询价
GM-26840AB-10 10 μg
GM-26840AB-100 100 μg
GM-26840AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Utomilumab
Source/Isotype Monoclonal human IgG2, λ
Application Flow cytometry
Specificity Detects 4-1BB
Gene 4-1BB
Other Names 4-1BB, CD137, CDw137, ILA, IMD109
Gene ID 3604(human), 102127961(cynomolgus)
Storage TNFRSF9 is a member of the tumor necrosis factor receptor superfamily. It is also called 4-1BB or CD137. 4-1BB/CD137/TNFRSF9 is expressed in activated CD4+ and CD8+ T cells, natural killer cells and dendritic cells. The ligand 4-1BBL/CD137L/TNFSF9 on antigen presenting cells binds to 4-1BB/CD137/TNFRSF9 and costimulates the activation of T cells. The binding of agonistic antibodies to 4-1BB/CD137/TNFRSF9 also leads to costimulation for T cell activation. Studies have shown the effectiveness of targeting 4-1BB/CD137/TNFRSF9 by its agonistic antibodies in cancer immunotherapy.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
产品编号：GM-26840AB
产品名称：Anti-H_4-1BB hIgG2 Antibody(Utomilumab)
目录价：询价
GM-26840AB-10 10 μg
GM-26840AB-100 100 μg
GM-26840AB-1000 1mg
Species Reactivity Human; Cynomolgus
Clone Utomilumab
Source/Isotype Monoclonal human IgG2, λ
Application Flow cytometry
Specificity Detects 4-1BB
Gene 4-1BB
Other Names 4-1BB, CD137, CDw137, ILA, IMD109
Gene ID 3604(human), 102127961(cynomolgus)
Storage TNFRSF9 is a member of the tumor necrosis factor receptor superfamily. It is also called 4-1BB or CD137. 4-1BB/CD137/TNFRSF9 is expressed in activated CD4+ and CD8+ T cells, natural killer cells and dendritic cells. The ligand 4-1BBL/CD137L/TNFSF9 on antigen presenting cells binds to 4-1BB/CD137/TNFRSF9 and costimulates the activation of T cells. The binding of agonistic antibodies to 4-1BB/CD137/TNFRSF9 also leads to costimulation for T cell activation. Studies have shown the effectiveness of targeting 4-1BB/CD137/TNFRSF9 by its agonistic antibodies in cancer immunotherapy.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
