产品编号：GM-87799MAB
产品名称：Anti-OX40L hIgG4 Reference Antibody (Amlbio)
目录价：询价
产品编号：GM-87799MAB
产品名称：Anti-OX40L hIgG4 Reference Antibody (Amlbio)
目录价：询价
GM-87799MAB-1mg / 1 mg
GM-87799MAB-5mg / 5 mg
GM-87799MAB-25mg / 25 mg
GM-87799MAB-50mg / 50mg
GM-87799MAB-100mg / 100mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target OX40L
Clone Amlitelimab
Alternative Names GP34; CD252; OX4OL; TXGP1; CD134L; OX-40L; TNLG2B
Source/Isotype Human IgG4 (S228P/ L235E), Kappa
Application /
Description OX40, also known as CD134 and Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels. OX40L binds to OX40 receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response beyond the first few days and onwards to a memory response due to its ability to enhance survival. OX40 also plays a crucial role in both Th1 and Th2 mediated reactions in vivo.
Formulation Phosphate-buffered solution, pH 7.4.
产品编号：GM-87799MAB
产品名称：Anti-OX40L hIgG4 Reference Antibody (Amlbio)
目录价：询价
GM-87799MAB-1mg / 1 mg
GM-87799MAB-5mg / 5 mg
GM-87799MAB-25mg / 25 mg
GM-87799MAB-50mg / 50mg
GM-87799MAB-100mg / 100mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target OX40L
Clone Amlitelimab
Alternative Names GP34; CD252; OX4OL; TXGP1; CD134L; OX-40L; TNLG2B
Source/Isotype Human IgG4 (S228P/ L235E), Kappa
Application /
Description OX40, also known as CD134 and Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels. OX40L binds to OX40 receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response beyond the first few days and onwards to a memory response due to its ability to enhance survival. OX40 also plays a crucial role in both Th1 and Th2 mediated reactions in vivo.
Formulation Phosphate-buffered solution, pH 7.4.
