产品编号：GM-87697AB
产品名称：Anti-NPR1 hIgG4 Antibody(REGN-5381)
目录价：询价
产品编号：GM-87697AB
产品名称：Anti-NPR1 hIgG4 Antibody(REGN-5381)
目录价：询价
GM-87697AB-10 10 μg
GM-87697AB-100 100 μg
GM-87697AB-1000 1mg
Species Reactivity Human
Clone REGN-5381
Source/Isotype Monoclonal Human IgG4,κ
Application Flow Cytometry
Specificity Detects NPR1
Gene NPR1
Other Names ANPRA, ANPa, GUC2A, GUCY2A, NPRA
Gene ID 4881(human);
Background Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms. The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2).which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP) and BNP, respectively).
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
产品编号：GM-87697AB
产品名称：Anti-NPR1 hIgG4 Antibody(REGN-5381)
目录价：询价
GM-87697AB-10 10 μg
GM-87697AB-100 100 μg
GM-87697AB-1000 1mg
Species Reactivity Human
Clone REGN-5381
Source/Isotype Monoclonal Human IgG4,κ
Application Flow Cytometry
Specificity Detects NPR1
Gene NPR1
Other Names ANPRA, ANPa, GUC2A, GUCY2A, NPRA
Gene ID 4881(human);
Background Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms. The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2).which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP) and BNP, respectively).
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
