产品编号：GM-86950AB
产品名称：Anti-Mouse PD-L1 mIgG1 Antibody(10F.9G2)
目录价：询价
产品编号：GM-86950AB
产品名称：Anti-Mouse PD-L1 mIgG1 Antibody(10F.9G2)
目录价：询价
GM-86950AB-1mg / 1 mg
GM-86950AB-5mg / 5 mg
GM-86950AB-25mg / 25 mg
GM-86950AB-50mg / 50 mg
GM-86950AB-100mg / 100 mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target PD-L1
Clone 10F.9G2
Alternative Names B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1
Source/Isotype Monoclonal Mouse IgG1 D265A，kappa
Description This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Formulation Phosphate-buffered solution, pH 7.2.
产品编号：GM-86950AB
产品名称：Anti-Mouse PD-L1 mIgG1 Antibody(10F.9G2)
目录价：询价
GM-86950AB-1mg / 1 mg
GM-86950AB-5mg / 5 mg
GM-86950AB-25mg / 25 mg
GM-86950AB-50mg / 50 mg
GM-86950AB-100mg / 100 mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target PD-L1
Clone 10F.9G2
Alternative Names B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1
Source/Isotype Monoclonal Mouse IgG1 D265A，kappa
Description This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Formulation Phosphate-buffered solution, pH 7.2.
