产品编号：GM-87801MAB
产品名称：Anti-CTLA4 hIgG1 Reference Antibody (Ipibio)
目录价：询价
产品编号：GM-87801MAB
产品名称：Anti-CTLA4 hIgG1 Reference Antibody (Ipibio)
目录价：询价
GM-87801MAB-1mg / 1 mg
GM-87801MAB-5mg / 5 mg
GM-87801MAB-25mg / 25 mg
GM-87801MAB-50mg / 50mg
GM-87801MAB-100mg / 100mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target CTLA4
Clone Ipilimumab
Alternative Names CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
Source/Isotype Monoclonal Human IgG1(RDEL),Kappa
Application /
Description This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Formulation Phosphate-buffered solution, pH 7.4.
产品编号：GM-87801MAB
产品名称：Anti-CTLA4 hIgG1 Reference Antibody (Ipibio)
目录价：询价
GM-87801MAB-1mg / 1 mg
GM-87801MAB-5mg / 5 mg
GM-87801MAB-25mg / 25 mg
GM-87801MAB-50mg / 50mg
GM-87801MAB-100mg / 100mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target CTLA4
Clone Ipilimumab
Alternative Names CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
Source/Isotype Monoclonal Human IgG1(RDEL),Kappa
Application /
Description This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Formulation Phosphate-buffered solution, pH 7.4.
