产品编号：GM-87808MAB
产品名称：Anti-EGFR hIgG1 Reference Antibody (Necbio)
目录价：询价
产品编号：GM-87808MAB
产品名称：Anti-EGFR hIgG1 Reference Antibody (Necbio)
目录价：询价
GM-87808MAB-1mg / 1 mg
GM-87808MAB-5mg / 5 mg
GM-87808MAB-25mg / 25 mg
GM-87808MAB-50mg / 50mg
GM-87808MAB-100mg / 100 mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target EGFR
Clone Necitumumab
Alternative Names ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA
Source/Isotype Human IgG1(REEM), Kappa
Application /
Description The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). In many cancer types, mutations affecting EGFR expression or activity could result in cancer. Deficient signaling of the EGFR and other receptor tyrosine kinases in humans is associated with diseases such as Alzheimer's, while over-expression is associated with the development of a wide variety of tumors. Interruption of EGFR signalling, either by blocking EGFR binding sites on the extracellular domain of the receptor or by inhibiting intracellular tyrosine kinase activity, can prevent the growth of EGFR-expressing tumours and improve the patient's condition.
Formulation Phosphate-buffered solution, pH 7.4.
产品编号：GM-87808MAB
产品名称：Anti-EGFR hIgG1 Reference Antibody (Necbio)
目录价：询价
GM-87808MAB-1mg / 1 mg
GM-87808MAB-5mg / 5 mg
GM-87808MAB-25mg / 25 mg
GM-87808MAB-50mg / 50mg
GM-87808MAB-100mg / 100 mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target EGFR
Clone Necitumumab
Alternative Names ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA
Source/Isotype Human IgG1(REEM), Kappa
Application /
Description The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). In many cancer types, mutations affecting EGFR expression or activity could result in cancer. Deficient signaling of the EGFR and other receptor tyrosine kinases in humans is associated with diseases such as Alzheimer's, while over-expression is associated with the development of a wide variety of tumors. Interruption of EGFR signalling, either by blocking EGFR binding sites on the extracellular domain of the receptor or by inhibiting intracellular tyrosine kinase activity, can prevent the growth of EGFR-expressing tumours and improve the patient's condition.
Formulation Phosphate-buffered solution, pH 7.4.
