当前位置:产品中心 > 抗体 > Biosimilar抗体 > TAA > Anti-DLL3 hIgG1 Reference Antibody (Rovabio)
Anti-DLL3 hIgG1 Reference Antibody (Rovabio)
基本信息

产品编号:GM-87163MAB

产品名称:Anti-DLL3 hIgG1 Reference Antibody (Rovabio)

目录价:询价


产品配图.jpg


规格货号

GM-87163MAB-1mg / 1 mg

GM-87163MAB-5mg / 5 mg

GM-87163MAB-25mg / 25 mg

GM-87163MAB-50mg / 50mg

GM-87163MAB-100mg / 100 mg



产品简介

Expression System     CHO

Aggregation               < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                   < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          DLL3

Clone                             Rovalpituzumab

Alternative Names       SCDO1

Source/Isotype           Human IgG1(KDEL,delta 447K), Kappa

Application                 Flow cytometry

Description                   Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Expression of DLL3 is highest in fetal brain. It plays a key role in somitogenesis within the Paraxial mesoderm. Mutations in this gene cause the autosomal recessive genetic disorder Jarcho-Levin syndrome. Expression of the gene occurs in Neuroendocrine tumors, which has been targeted as a potential pathway for treatment. An experimental drug, rovalpituzumab tesirine, targets DLL3 as a possible treatment for lung cancer.

Formulation                Phosphate-buffered solution, pH 7.4.



数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-DLL3 hIgG1 Reference Antibody (Rovabio)

Anti-DLL3 hIgG1 Reference Antibody (Rovabio)
基本信息

产品编号:GM-87163MAB

产品名称:Anti-DLL3 hIgG1 Reference Antibody (Rovabio)

目录价:询价


产品配图.jpg


规格货号

GM-87163MAB-1mg / 1 mg

GM-87163MAB-5mg / 5 mg

GM-87163MAB-25mg / 25 mg

GM-87163MAB-50mg / 50mg

GM-87163MAB-100mg / 100 mg



产品简介

Expression System     CHO

Aggregation               < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                   < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          DLL3

Clone                             Rovalpituzumab

Alternative Names       SCDO1

Source/Isotype           Human IgG1(KDEL,delta 447K), Kappa

Application                 Flow cytometry

Description                   Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Expression of DLL3 is highest in fetal brain. It plays a key role in somitogenesis within the Paraxial mesoderm. Mutations in this gene cause the autosomal recessive genetic disorder Jarcho-Levin syndrome. Expression of the gene occurs in Neuroendocrine tumors, which has been targeted as a potential pathway for treatment. An experimental drug, rovalpituzumab tesirine, targets DLL3 as a possible treatment for lung cancer.

Formulation                Phosphate-buffered solution, pH 7.4.



数据展示

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image.png

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