当前位置:产品中心 > 抗体 > Biosimilar抗体 > TAA > Anti-CD22 hIgG4 Reference Antibody (Inobio)
Anti-CD22 hIgG4 Reference Antibody (Inobio)
基本信息

产品编号:GM-87699MAB

产品名称:Anti-CD22 hIgG4 Reference Antibody (Inobio)

目录价:询价


产品配图.jpg


规格货号

GM-87699MAB-1mg / 1 mg

GM-87699MAB-5mg / 5 mg

GM-87699MAB-25mg / 25 mg

GM-87699MAB-50mg / 50 mg

GM-87699MAB-100mg / 100mg



产品简介

Expression System      CHO

Aggregation                < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          CD22

Clone                               Inotuzumab

Alternative Names         SIGLEC-2, SIGLEC2

Source/Isotype           Human IgG4 (S228P), Kappa

Application                 /

Description                    CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. In mice, it has been shown that CD22 blockade restores homeostatic microglial phagocytosis in aging brains

Formulation                   phosphate-buffered solution, pH 7.4.


数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-CD22 hIgG4 Reference Antibody (Inobio)

Anti-CD22 hIgG4 Reference Antibody (Inobio)
基本信息

产品编号:GM-87699MAB

产品名称:Anti-CD22 hIgG4 Reference Antibody (Inobio)

目录价:询价


产品配图.jpg


规格货号

GM-87699MAB-1mg / 1 mg

GM-87699MAB-5mg / 5 mg

GM-87699MAB-25mg / 25 mg

GM-87699MAB-50mg / 50 mg

GM-87699MAB-100mg / 100mg



产品简介

Expression System      CHO

Aggregation                < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          CD22

Clone                               Inotuzumab

Alternative Names         SIGLEC-2, SIGLEC2

Source/Isotype           Human IgG4 (S228P), Kappa

Application                 /

Description                    CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. In mice, it has been shown that CD22 blockade restores homeostatic microglial phagocytosis in aging brains

Formulation                   phosphate-buffered solution, pH 7.4.


数据展示

image.png

image.png


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