产品编号：GM-87699MAB
产品名称：Anti-CD22 hIgG4 Reference Antibody (Inobio)
目录价：询价
产品编号：GM-87699MAB
产品名称：Anti-CD22 hIgG4 Reference Antibody (Inobio)
目录价：询价
GM-87699MAB-1mg / 1 mg
GM-87699MAB-5mg / 5 mg
GM-87699MAB-25mg / 25 mg
GM-87699MAB-50mg / 50 mg
GM-87699MAB-100mg / 100mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target CD22
Clone Inotuzumab
Alternative Names SIGLEC-2, SIGLEC2
Source/Isotype Human IgG4 (S228P), Kappa
Application /
Description CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. In mice, it has been shown that CD22 blockade restores homeostatic microglial phagocytosis in aging brains
Formulation phosphate-buffered solution, pH 7.4.
产品编号：GM-87699MAB
产品名称：Anti-CD22 hIgG4 Reference Antibody (Inobio)
目录价：询价
GM-87699MAB-1mg / 1 mg
GM-87699MAB-5mg / 5 mg
GM-87699MAB-25mg / 25 mg
GM-87699MAB-50mg / 50 mg
GM-87699MAB-100mg / 100mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target CD22
Clone Inotuzumab
Alternative Names SIGLEC-2, SIGLEC2
Source/Isotype Human IgG4 (S228P), Kappa
Application /
Description CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. In mice, it has been shown that CD22 blockade restores homeostatic microglial phagocytosis in aging brains
Formulation phosphate-buffered solution, pH 7.4.
