当前位置:产品中心 > 抗体 > Biosimilar抗体 > TAA > Anti-SLC34A2 hIgG1 Reference Antibody (Upibio)
Anti-SLC34A2 hIgG1 Reference Antibody (Upibio)
基本信息

产品编号:GM-86855MAB

产品名称:Anti-SLC34A2 hIgG1 Reference Antibody (Upibio)

目录价:询价


产品配图.jpg


规格货号

GM-86855MAB-1mg / 1 mg

GM-86855MAB-5mg / 5 mg

GM-86855MAB-25mg / 25 mg

GM-86855MAB-50mg / 50 mg

GM-86855MAB-100mg / 100mg



产品简介

Expression System      CHO

Aggregation                < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          SLC34A2

Clone                           Upifitamab

Alternative Names     NAPI-3B, NAPI-IIb, NPTIIb, PULAM

Source/Isotype           Human IgG1(REEM),kappa

Application                 Flow cytometry

Description                 Solute carrier family 34 member A2 (SLC34A2), also known as NaPi2b, pH-sensitive sodium-dependent phosphate transporter, which belongs to the solute carrier (SLC) family. The SLC34 family consists of three sodium-dependent phosphate transporters, A1, A2, and A3, that carry the monovalent form phosphate into cells. SLC34A2 is a sodium dependent inorganic phosphate (Pi) transporter that regulates phosphate homeostasis in various organs, including the small intestine, lung, liver, and testis. In the small intestine, NaPi-2b localizes to the intestinal brush border membrane to mediate Pi reabsorption. In the lung, NaPi-2b is expressed in the apical membrane of type II alveolar cells and is involved in the synthesis of surfactant. Mutations in the corresponding SLC34A2 gene causes pulmonary alveolar microlithiasis, a rare autosomal recessive disorder characterized by the deposition of calcium phosphate microliths throughout the lungs. Research studies show aberrant expression of NaPi-2b in various type of cancer, including ovarian, breast, and lung cancer. Chromosomal rearrangements involving SLC34A2-ROS1 are seen in gastric.

Formulation                phosphate-buffered solution, pH 7.4.


数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-SLC34A2 hIgG1 Reference Antibody (Upibio)

Anti-SLC34A2 hIgG1 Reference Antibody (Upibio)
基本信息

产品编号:GM-86855MAB

产品名称:Anti-SLC34A2 hIgG1 Reference Antibody (Upibio)

目录价:询价


产品配图.jpg


规格货号

GM-86855MAB-1mg / 1 mg

GM-86855MAB-5mg / 5 mg

GM-86855MAB-25mg / 25 mg

GM-86855MAB-50mg / 50 mg

GM-86855MAB-100mg / 100mg



产品简介

Expression System      CHO

Aggregation                < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          SLC34A2

Clone                           Upifitamab

Alternative Names     NAPI-3B, NAPI-IIb, NPTIIb, PULAM

Source/Isotype           Human IgG1(REEM),kappa

Application                 Flow cytometry

Description                 Solute carrier family 34 member A2 (SLC34A2), also known as NaPi2b, pH-sensitive sodium-dependent phosphate transporter, which belongs to the solute carrier (SLC) family. The SLC34 family consists of three sodium-dependent phosphate transporters, A1, A2, and A3, that carry the monovalent form phosphate into cells. SLC34A2 is a sodium dependent inorganic phosphate (Pi) transporter that regulates phosphate homeostasis in various organs, including the small intestine, lung, liver, and testis. In the small intestine, NaPi-2b localizes to the intestinal brush border membrane to mediate Pi reabsorption. In the lung, NaPi-2b is expressed in the apical membrane of type II alveolar cells and is involved in the synthesis of surfactant. Mutations in the corresponding SLC34A2 gene causes pulmonary alveolar microlithiasis, a rare autosomal recessive disorder characterized by the deposition of calcium phosphate microliths throughout the lungs. Research studies show aberrant expression of NaPi-2b in various type of cancer, including ovarian, breast, and lung cancer. Chromosomal rearrangements involving SLC34A2-ROS1 are seen in gastric.

Formulation                phosphate-buffered solution, pH 7.4.


数据展示

image.png

image.png

image.png

image.png

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