产品编号：GM-88096MAB
产品名称：Anti-CLDN1 hIgG1 Reference Antibody (Lixubio)
目录价：询价
产品编号：GM-88096MAB
产品名称：Anti-CLDN1 hIgG1 Reference Antibody (Lixubio)
目录价：询价
GM-88096MAB-1mg / 1 mg
GM-88096MAB-5mg / 5 mg
GM-88096MAB-25mg / 5 mg * 5 vials
GM-88096MAB-50mg / 50 mg
GM-88096MAB-100mg / 50 mg * 2 vials
Expression System | CHO |
Aggregation | < 5% as determined by SEC-HPLC |
Purity | > 95% as determined by SDS-PAGE |
Species Reactivity | Human |
Clone | Lixudebart |
Source/Isotype | Monoclonal Human IgG1 REEM,P330S,Delta447K |
Application | Flow Cytometry |
Specificity | Detects CLDN1 |
Gene | CLDN1 |
Other Names | CLD1, ILVASC, SEMP |
Gene ID | 9076 (human) |
Background | CLDN1(Claudin-1) is an important component of cell-cell junctions. It belongs to the cell adhesion protein family and is mainly expressed in epithelial cells. Claudin-1 is expressed in many types of epithelial cells and plays a key role in regulating cell permeability and establishing biological barriers. It plays a key role in maintaining the barrier function of cells and participating in cell signal transduction. Lixudebart is a humanized IgG1 monoclonal antibody developed by Alentis Therapeutics that targets the Claudin-1 protein and is used to treat diseases such as kidney, liver and lung fibrosis. In the treatment of ANCA-associated vasculitis and other fibrosis-related diseases, it can be used as an emerging targeted therapy in combination with traditional drugs to optimize the treatment effect. |
Storage | Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
产品编号：GM-88096MAB
产品名称：Anti-CLDN1 hIgG1 Reference Antibody (Lixubio)
目录价：询价
GM-88096MAB-1mg / 1 mg
GM-88096MAB-5mg / 5 mg
GM-88096MAB-25mg / 5 mg * 5 vials
GM-88096MAB-50mg / 50 mg
GM-88096MAB-100mg / 50 mg * 2 vials
Expression System | CHO |
Aggregation | < 5% as determined by SEC-HPLC |
Purity | > 95% as determined by SDS-PAGE |
Species Reactivity | Human |
Clone | Lixudebart |
Source/Isotype | Monoclonal Human IgG1 REEM,P330S,Delta447K |
Application | Flow Cytometry |
Specificity | Detects CLDN1 |
Gene | CLDN1 |
Other Names | CLD1, ILVASC, SEMP |
Gene ID | 9076 (human) |
Background | CLDN1(Claudin-1) is an important component of cell-cell junctions. It belongs to the cell adhesion protein family and is mainly expressed in epithelial cells. Claudin-1 is expressed in many types of epithelial cells and plays a key role in regulating cell permeability and establishing biological barriers. It plays a key role in maintaining the barrier function of cells and participating in cell signal transduction. Lixudebart is a humanized IgG1 monoclonal antibody developed by Alentis Therapeutics that targets the Claudin-1 protein and is used to treat diseases such as kidney, liver and lung fibrosis. In the treatment of ANCA-associated vasculitis and other fibrosis-related diseases, it can be used as an emerging targeted therapy in combination with traditional drugs to optimize the treatment effect. |
Storage | Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
