当前位置:产品中心 > 抗体 > Biosimilar抗体 > 细胞因子 > Anti-ACVR2B hIgG1 Antibody(Bimagrumab)
Anti-ACVR2B hIgG1 Antibody(Bimagrumab)
基本信息

产品编号:GM-51148AB

产品名称:Anti-ACVR2B hIgG1 Antibody(Bimagrumab)

目录价:询价


产品配图.jpg


规格货号

GM-51148AB-10           10 μg

GM-51148AB-100         100 μg

GM-51148AB-1000       1mg



产品简介

Species Reactivity      Human

Clone                           Bimagrumab

Source/Isotype           Monoclonal Human IgG1/λ

Application                 Flow Cytometry; Block assay; ELISA

Specificity                   Detects ACVR2B

Gene                            ACVR2B

Other Names              HTX4; ACTRIIB; ActR-IIB

Gene ID                       Q13705

Background                ACVR2B is an activin type 2 receptor.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. ACVR2B binds to activin and growth differentiation factor (GDF), which in turn activates type I receptors ansd activates downstream molecules. In addition, mutations in this gene may affect protein function in left and right axis formation and cardiovascular development, as well as reduce muscle mass and bone mass.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay



数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-ACVR2B hIgG1 Antibody(Bimagrumab)

Anti-ACVR2B hIgG1 Antibody(Bimagrumab)
基本信息

产品编号:GM-51148AB

产品名称:Anti-ACVR2B hIgG1 Antibody(Bimagrumab)

目录价:询价


产品配图.jpg


规格货号

GM-51148AB-10           10 μg

GM-51148AB-100         100 μg

GM-51148AB-1000       1mg



产品简介

Species Reactivity      Human

Clone                           Bimagrumab

Source/Isotype           Monoclonal Human IgG1/λ

Application                 Flow Cytometry; Block assay; ELISA

Specificity                   Detects ACVR2B

Gene                            ACVR2B

Other Names              HTX4; ACTRIIB; ActR-IIB

Gene ID                       Q13705

Background                ACVR2B is an activin type 2 receptor.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. ACVR2B binds to activin and growth differentiation factor (GDF), which in turn activates type I receptors ansd activates downstream molecules. In addition, mutations in this gene may affect protein function in left and right axis formation and cardiovascular development, as well as reduce muscle mass and bone mass.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay



数据展示

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image.png

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image.pngimage.png

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