当前位置:产品中心 > 抗体 > Biosimilar抗体 > 细胞因子 > Anti-ACVR2B mIgG2a Antibody(Bimagrumab)
Anti-ACVR2B mIgG2a Antibody(Bimagrumab)
基本信息

产品编号:GM-87700AB

产品名称:Anti-ACVR2B mIgG2a Antibody(Bimagrumab)

目录价:询价

产品配图.jpg


规格货号

GM-87700AB-10        10 μg

GM-87700AB-100      100 μg

GM-87700AB-1000    1 mg



产品简介

Species Reactivity      Human

Clone                          Bimagrumab

Source/Isotype          Monoclonal mouse IgG2a, κ

Application                Bioactivity-ELISA

Specificity                  Detects ACVR2B

Gene                           ACVR2B

Other Names             ACTRIIB, ActR-IIB, HTX4

Gene ID                      93(human)

Background               ACVR2B is an activin type 2 receptor.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. ACVR2B binds to activin and growth differentiation factor (GDF), which in turn activates type I receptors ansd activates downstream molecules. In addition, mutations in this gene may affect protein function in left and right axis formation and cardiovascular development, as well as reduce muscle mass and bone mass.

Storage                       Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation               Phosphate-buffered solution, pH 7.2.

Endotoxin                   < 1 EU/mg, determined by LAL gel clotting assay



数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-ACVR2B mIgG2a Antibody(Bimagrumab)

Anti-ACVR2B mIgG2a Antibody(Bimagrumab)
基本信息

产品编号:GM-87700AB

产品名称:Anti-ACVR2B mIgG2a Antibody(Bimagrumab)

目录价:询价

产品配图.jpg


规格货号

GM-87700AB-10        10 μg

GM-87700AB-100      100 μg

GM-87700AB-1000    1 mg



产品简介

Species Reactivity      Human

Clone                          Bimagrumab

Source/Isotype          Monoclonal mouse IgG2a, κ

Application                Bioactivity-ELISA

Specificity                  Detects ACVR2B

Gene                           ACVR2B

Other Names             ACTRIIB, ActR-IIB, HTX4

Gene ID                      93(human)

Background               ACVR2B is an activin type 2 receptor.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. ACVR2B binds to activin and growth differentiation factor (GDF), which in turn activates type I receptors ansd activates downstream molecules. In addition, mutations in this gene may affect protein function in left and right axis formation and cardiovascular development, as well as reduce muscle mass and bone mass.

Storage                       Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation               Phosphate-buffered solution, pH 7.2.

Endotoxin                   < 1 EU/mg, determined by LAL gel clotting assay



数据展示

image.png

image.png

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