当前位置:产品中心 > 抗体 > Biosimilar抗体 > 免疫检查点 > Anti-H_CD40L hIgG1 Antibody(dapirolizumab)
Anti-H_CD40L hIgG1 Antibody(dapirolizumab)
基本信息

产品编号:GM-83977AB

产品名称:Anti-H_CD40L hIgG1 Antibody(dapirolizumab)

目录价:询价


/ueditor/image/20240514/1715663675884583/efcf44a9ceeaae84307ca377d39eef4e.jpg

规格货号

GM-83977AB-10           10 μg

GM-83977AB-100         100 μg

GM-83977AB-1000       1mg

产品简介

Species Reactivity      Human; Cynomolgus

Clone                           dapirolizumab

Source/Isotype           Monoclonal Human IgG1/κ

Application                 Flow cytometry; Block assay ;ELISA

Specificity                   Detects  CD40L

Gene                            CD40L

Other Names              CD40LG,CD154,CD40L,HIGM1,IGM,IMD3,T-BAM,TNFSF5,TRAP,gp39.

Gene ID                       P29965 (human); G7Q1T4 (cynomolgus)

Background                CD40 ligand (CD40LG) is a type II transmembrane glycoprotein belonging to the TNF superfamily. Initially discovered on the surface of CD4+ T cells following T cell receptor activation, CD40LG exists in both membrane-bound and soluble trimeric forms. CD40LG serves as the ligand for CD40, and its binding initiates signal transduction in cells expressing CD40LG. CD40LG is a differentiation antigen expressed on the surface of T cells. In the presence of cytokines, it stimulates B cell proliferation and the secretion of all immunoglobulin isotypes. CD40LG has been shown to induce cytokine production and tumor cell killing. It is also known by the aliases CD154, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, and gp39.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

数据

/ueditor/image/20240514/1715663861261929/0cde81a6e68287a6e05086a93077de24.png

/ueditor/image/20240514/1715663894312731/88aa852a1989f8af056c0be821e183df.png

GM-83977AB-3.png


GM-83977AB-4.png


/ueditor/image/20240514/1715664439913145/93196e37845d351d7241ce4316bf295e.png

当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-H_CD40L hIgG1 Antibody(dapirolizumab)

Anti-H_CD40L hIgG1 Antibody(dapirolizumab)
基本信息

产品编号:GM-83977AB

产品名称:Anti-H_CD40L hIgG1 Antibody(dapirolizumab)

目录价:询价


/ueditor/image/20240514/1715663675884583/efcf44a9ceeaae84307ca377d39eef4e.jpg

规格货号

GM-83977AB-10           10 μg

GM-83977AB-100         100 μg

GM-83977AB-1000       1mg

产品简介

Species Reactivity      Human; Cynomolgus

Clone                           dapirolizumab

Source/Isotype           Monoclonal Human IgG1/κ

Application                 Flow cytometry; Block assay ;ELISA

Specificity                   Detects  CD40L

Gene                            CD40L

Other Names              CD40LG,CD154,CD40L,HIGM1,IGM,IMD3,T-BAM,TNFSF5,TRAP,gp39.

Gene ID                       P29965 (human); G7Q1T4 (cynomolgus)

Background                CD40 ligand (CD40LG) is a type II transmembrane glycoprotein belonging to the TNF superfamily. Initially discovered on the surface of CD4+ T cells following T cell receptor activation, CD40LG exists in both membrane-bound and soluble trimeric forms. CD40LG serves as the ligand for CD40, and its binding initiates signal transduction in cells expressing CD40LG. CD40LG is a differentiation antigen expressed on the surface of T cells. In the presence of cytokines, it stimulates B cell proliferation and the secretion of all immunoglobulin isotypes. CD40LG has been shown to induce cytokine production and tumor cell killing. It is also known by the aliases CD154, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, and gp39.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

数据

/ueditor/image/20240514/1715663861261929/0cde81a6e68287a6e05086a93077de24.png

/ueditor/image/20240514/1715663894312731/88aa852a1989f8af056c0be821e183df.png

GM-83977AB-3.png


GM-83977AB-4.png


/ueditor/image/20240514/1715664439913145/93196e37845d351d7241ce4316bf295e.png

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