当前位置:产品中心 > 抗体 > Biosimilar抗体 > 免疫 > Anti- H_MS4A1(CD20) hIgG1 Antibody(Ocrelizumab)
Anti- H_MS4A1(CD20) hIgG1 Antibody(Ocrelizumab)
基本信息

产品编号:GM-27200AB

产品名称:Anti- H_MS4A1(CD20) hIgG1 Antibody(Ocrelizumab)

目录价:询价


产品配图.jpg


规格货号

GM-27200AB-10         10 μg

GM-27200AB-100       100 μg

GM-27200AB-1000     1 mg

产品简介

Species Reactivity       Human

Clone                           Ocrelizumab

Source/Isotype           Monoclonal human IgG1, κ

Application                 Flow cytometry

Specificity                   Detects CD20

Gene                            MS4A1

Other Names              B1, Bp35, CVID5, FMC7, LEU-16, S7

Gene ID                       931

Background               B-lymphocyte antigen CD20 or CD20 is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. In humans CD20 is encoded by the MS4A1 gene. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. Immunohistochemistry can be used to determine the presence of CD20 on cells in histological tissue sections. Because CD20 remains present on the cells of most B-cell neoplasms,and is absent on otherwise similar appearing T-cell neoplasms, it can be very useful in diagnosing conditions such as B-cell lymphomas and leukaemias. However, the presence or absence of CD20 in such tumours is not relevant to prognosis, with the progression of the disease being much the same in either case. CD20 positive cells are also sometimes found in cases of Hodgkins disease, myeloma, and thymoma.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti- H_MS4A1(CD20) hIgG1 Antibody(Ocrelizumab)

Anti- H_MS4A1(CD20) hIgG1 Antibody(Ocrelizumab)
基本信息

产品编号:GM-27200AB

产品名称:Anti- H_MS4A1(CD20) hIgG1 Antibody(Ocrelizumab)

目录价:询价


产品配图.jpg


规格货号

GM-27200AB-10         10 μg

GM-27200AB-100       100 μg

GM-27200AB-1000     1 mg

产品简介

Species Reactivity       Human

Clone                           Ocrelizumab

Source/Isotype           Monoclonal human IgG1, κ

Application                 Flow cytometry

Specificity                   Detects CD20

Gene                            MS4A1

Other Names              B1, Bp35, CVID5, FMC7, LEU-16, S7

Gene ID                       931

Background               B-lymphocyte antigen CD20 or CD20 is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. In humans CD20 is encoded by the MS4A1 gene. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. Immunohistochemistry can be used to determine the presence of CD20 on cells in histological tissue sections. Because CD20 remains present on the cells of most B-cell neoplasms,and is absent on otherwise similar appearing T-cell neoplasms, it can be very useful in diagnosing conditions such as B-cell lymphomas and leukaemias. However, the presence or absence of CD20 in such tumours is not relevant to prognosis, with the progression of the disease being much the same in either case. CD20 positive cells are also sometimes found in cases of Hodgkins disease, myeloma, and thymoma.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


数据展示

/ueditor/image/20240515/1715751782467600/661ddbbad716e0c19c6871614077b37c.png

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