当前位置:产品中心 > 抗体 > Biosimilar抗体 > TNF > Anti-H_TNFSF15(TL1A) hIgG1 Antibody(PF-06480605)
Anti-H_TNFSF15(TL1A) hIgG1 Antibody(PF-06480605)
基本信息

产品编号:GM-59479AB

产品名称:Anti-H_TNFSF15(TL1A) hIgG1 Antibody(PF-06480605)

目录价:询价


产品配图.jpg


规格货号

GM-59479AB-10         10 μg

GM-59479AB-100       100 μg

GM-59479AB-1000     1 mg

产品简介

Species Reactivity      Human; Mouse


Clone                           PF-06480605


Source/Isotype           Monoclonal Human IgG1 /κ


Application                 Flow cytometry;Block assay


Specificity                   Detects TNFSF15(TL1A).


Gene                            TNFSF15(TL1A)


Other Names              TL1; TL1A; VEGI; TNLG1B; VEGI192A


Gene ID                       O95150 (Human); Q5UBV8 (Mouse)


Background                The protein encoded by TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells but is not expressed in either B or T cells. The expression of this protein is inducible by TNF-alpha and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 (death receptor 3) and TNFRSF6B (decoy receptor 3). It can activate both the NF-κB and MAPK signalling pathways and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


数据展示

/ueditor/image/20240515/1715764241808982/0fc13ea77957db979384ed4bb1869406.png

/ueditor/image/20240515/1715764279207992/74f71377dd4293b9f5ac1ae5849fba74.png


/ueditor/image/20240515/1715764386680771/ba56363d8957f6472dfae73cd9931b10.png



/ueditor/image/20240515/1715764458585522/5984032a98448ab1d6f6bc552e412a1c.png




当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-H_TNFSF15(TL1A) hIgG1 Antibody(PF-06480605)

Anti-H_TNFSF15(TL1A) hIgG1 Antibody(PF-06480605)
基本信息

产品编号:GM-59479AB

产品名称:Anti-H_TNFSF15(TL1A) hIgG1 Antibody(PF-06480605)

目录价:询价


产品配图.jpg


规格货号

GM-59479AB-10         10 μg

GM-59479AB-100       100 μg

GM-59479AB-1000     1 mg

产品简介

Species Reactivity      Human; Mouse


Clone                           PF-06480605


Source/Isotype           Monoclonal Human IgG1 /κ


Application                 Flow cytometry;Block assay


Specificity                   Detects TNFSF15(TL1A).


Gene                            TNFSF15(TL1A)


Other Names              TL1; TL1A; VEGI; TNLG1B; VEGI192A


Gene ID                       O95150 (Human); Q5UBV8 (Mouse)


Background                The protein encoded by TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells but is not expressed in either B or T cells. The expression of this protein is inducible by TNF-alpha and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 (death receptor 3) and TNFRSF6B (decoy receptor 3). It can activate both the NF-κB and MAPK signalling pathways and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


数据展示

/ueditor/image/20240515/1715764241808982/0fc13ea77957db979384ed4bb1869406.png

/ueditor/image/20240515/1715764279207992/74f71377dd4293b9f5ac1ae5849fba74.png


/ueditor/image/20240515/1715764386680771/ba56363d8957f6472dfae73cd9931b10.png



/ueditor/image/20240515/1715764458585522/5984032a98448ab1d6f6bc552e412a1c.png




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