当前位置:产品中心 > 抗体 > Biosimilar抗体 > TNF > Anti-TNF-α hIgG1 Antibody(CT-P17)
Anti-TNF-α hIgG1 Antibody(CT-P17)
基本信息

产品编号:GM-49267AB

产品名称:Anti-TNF-α hIgG1 Antibody(CT-P17)

目录价:询价


产品配图.jpg


规格货号

GM-49267AB-10        10 μg

GM-49267AB-100      100 μg

GM-49267AB-1000    1 mg

产品简介

Species Reactivity       Human

Clone                           CT-P17

Source/Isotype           Monoclonal Human IgG1,κ

Application                 Block assay

Specificity                   Detects TNF-α.

Gene                            TNF-α

Other Names              DIF; TNFA; TNFSF2; TNLG1F

Gene ID                       7124

Background                TNFα is expressed as a type II membrane protein attached by a signal anchor transmembrane domain in the propeptide, and is processed by a matrix metallo-proteinase, termed TNFα-converting enzyme (TACE). TNF is predominantly produced by macrophages, but can also be secreted in limited quantities by B cells, natural killer cells, endothelial and muscle cells, fibroblasts, and osteoclasts. TNF exists in a membrane-bound and a soluble form. During synthesis, TNF translocates to the cell membrane where the TNF-converting enzyme releases the membrane-bound 26 kDa molecule into the extracellular milieu as a 17 kDa protein. The activity of this enzyme not only releases TNF from the plasma membrane, but also cleaves TNF receptors off the surface, which act as an inhibitor of TNF action. Both membrane-bound and released TNF are active.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


数据展示

/ueditor/image/20240515/1715761976595174/54237d112fdd80fc85dc9ecab3c26303.png


当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-TNF-α hIgG1 Antibody(CT-P17)

Anti-TNF-α hIgG1 Antibody(CT-P17)
基本信息

产品编号:GM-49267AB

产品名称:Anti-TNF-α hIgG1 Antibody(CT-P17)

目录价:询价


产品配图.jpg


规格货号

GM-49267AB-10        10 μg

GM-49267AB-100      100 μg

GM-49267AB-1000    1 mg

产品简介

Species Reactivity       Human

Clone                           CT-P17

Source/Isotype           Monoclonal Human IgG1,κ

Application                 Block assay

Specificity                   Detects TNF-α.

Gene                            TNF-α

Other Names              DIF; TNFA; TNFSF2; TNLG1F

Gene ID                       7124

Background                TNFα is expressed as a type II membrane protein attached by a signal anchor transmembrane domain in the propeptide, and is processed by a matrix metallo-proteinase, termed TNFα-converting enzyme (TACE). TNF is predominantly produced by macrophages, but can also be secreted in limited quantities by B cells, natural killer cells, endothelial and muscle cells, fibroblasts, and osteoclasts. TNF exists in a membrane-bound and a soluble form. During synthesis, TNF translocates to the cell membrane where the TNF-converting enzyme releases the membrane-bound 26 kDa molecule into the extracellular milieu as a 17 kDa protein. The activity of this enzyme not only releases TNF from the plasma membrane, but also cleaves TNF receptors off the surface, which act as an inhibitor of TNF action. Both membrane-bound and released TNF are active.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay


数据展示

/ueditor/image/20240515/1715761976595174/54237d112fdd80fc85dc9ecab3c26303.png


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