当前位置:产品中心 > 抗体 > Biosimilar抗体 > TNF > Anti-TNFRSF25(DR3) hIgG1 Antibody(PTX-35)
Anti-TNFRSF25(DR3) hIgG1 Antibody(PTX-35)
基本信息

产品编号:GM-58913AB

产品名称:Anti-TNFRSF25(DR3) hIgG1 Antibody(PTX-35)

目录价:询价


产品配图.jpg


规格货号

GM-58913AB-10           10 μg

GM-58913AB-100         100 μg

GM-58913AB-1000       1mg


产品简介

Species Reactivity       Human; Mouse

Clone                           PTX-35

Source/Isotype           Monoclonal Human IgG1 /λ

Application                 Flow Cytometry; Activation assay

Specificity                   Detects TNFRSF25(DR3)

Gene                            TNFRSF25

Other Names              DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; GEF720; WSL-LR; PLEKHG5; TNFRSF12

Gene ID                       Q93038-1 (Human) ; Q8VD70 (Mouse)

Background                Death receptor 3 (DR3), also known as tumor necrosis factor receptor superfamily member 25 (TNFRSF25), is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially by activated and antigen-experienced T lymphocytes. TNFRSF25 is also highly expressed by FoxP3 positive regulatory T lymphocytes. TNFRSF25 is activated by a monogamous ligand, known as TL1A (TNFSF15), which is rapidly upregulated in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal both through the TRADD adaptor molecule to stimulate NF-kappa B activity or through the FADD adaptor molecule to stimulate caspase activation and regulate cell apoptosis.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay



数据展示

/ueditor/image/20240515/1715765795153893/e2aaa4f9bf7f5f616832fa9cae40f9f9.png

/ueditor/image/20240515/1715765810189129/de4e7978962ace2c4528dd38e2f0a867.png

/ueditor/image/20240515/1715765819675987/937645a7c0cc8e142a721c314f952c68.png

/ueditor/image/20240515/1715765991459280/82800a12c2348b4574229c1a73aeb96f.png

/ueditor/image/20240515/1715766019833106/566ba6489085355e0d07d88f4d343cf5.png



















当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-TNFRSF25(DR3) hIgG1 Antibody(PTX-35)

Anti-TNFRSF25(DR3) hIgG1 Antibody(PTX-35)
基本信息

产品编号:GM-58913AB

产品名称:Anti-TNFRSF25(DR3) hIgG1 Antibody(PTX-35)

目录价:询价


产品配图.jpg


规格货号

GM-58913AB-10           10 μg

GM-58913AB-100         100 μg

GM-58913AB-1000       1mg


产品简介

Species Reactivity       Human; Mouse

Clone                           PTX-35

Source/Isotype           Monoclonal Human IgG1 /λ

Application                 Flow Cytometry; Activation assay

Specificity                   Detects TNFRSF25(DR3)

Gene                            TNFRSF25

Other Names              DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; GEF720; WSL-LR; PLEKHG5; TNFRSF12

Gene ID                       Q93038-1 (Human) ; Q8VD70 (Mouse)

Background                Death receptor 3 (DR3), also known as tumor necrosis factor receptor superfamily member 25 (TNFRSF25), is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially by activated and antigen-experienced T lymphocytes. TNFRSF25 is also highly expressed by FoxP3 positive regulatory T lymphocytes. TNFRSF25 is activated by a monogamous ligand, known as TL1A (TNFSF15), which is rapidly upregulated in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal both through the TRADD adaptor molecule to stimulate NF-kappa B activity or through the FADD adaptor molecule to stimulate caspase activation and regulate cell apoptosis.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay



数据展示

/ueditor/image/20240515/1715765795153893/e2aaa4f9bf7f5f616832fa9cae40f9f9.png

/ueditor/image/20240515/1715765810189129/de4e7978962ace2c4528dd38e2f0a867.png

/ueditor/image/20240515/1715765819675987/937645a7c0cc8e142a721c314f952c68.png

/ueditor/image/20240515/1715765991459280/82800a12c2348b4574229c1a73aeb96f.png

/ueditor/image/20240515/1715766019833106/566ba6489085355e0d07d88f4d343cf5.png



















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