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H_TACI Reporter Cell Line
基本信息

产品编号:GM-C35041

产品名称:H_TACI Reporter Cell Line

目录价:询价

GM-C35041信号通路.png

细胞培养、冻存、复苏试剂准备

生长培养基:RPMI 1640+10% FBS+1% P.S+3.5 μg/mL Blasticidin+0.75 μg/mL Puromycin

细胞冻存液:90% FBS+10% DMSO

Assay Buffer:RPMI 1640+1% FBS+1% P.S

产品简介

TACI(Transmembrane Activator and CAML Interactor)是由TNFRSF13B基因编码的一种受体,属于肿瘤坏死因子受体超家族(TNF receptor superfamily)。主要存在于B细胞和浆细胞上,并在免疫系统的调控中发挥重要作用。


TACI胞外包含两个半胱氨酸富集结构域(CRD),这两个结构域负责与其主要配体BAFF(B-cell Activating Factor)和APRIL(A Proliferation-Inducing Ligand)结合,使得TACI能够特异性识别和结合配体,从而启动信号传导。TACI信号传导在B细胞的存活、成熟和抗体生成中起关键作用。


吉满生物H_TACI Reporter Cell Line是一种Luciferase报告基因细胞系。当BAFF结合TACI受体后,激活下游信号通路,从而激活荧光素酶(Luciferase)的表达。Luciferase读值即代表信号通路的激活效果,因此可用于TACI相关药物的体外效果评价。


数据展示
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当前位置:产品中心 > 细胞系 > TAA > BCMA:BAFFR:TACI > H_TACI Reporter Cell Line

H_TACI Reporter Cell Line
基本信息

产品编号:GM-C35041

产品名称:H_TACI Reporter Cell Line

目录价:询价

GM-C35041信号通路.png

细胞培养、冻存、复苏试剂准备

生长培养基:RPMI 1640+10% FBS+1% P.S+3.5 μg/mL Blasticidin+0.75 μg/mL Puromycin

细胞冻存液:90% FBS+10% DMSO

Assay Buffer:RPMI 1640+1% FBS+1% P.S

产品简介

TACI(Transmembrane Activator and CAML Interactor)是由TNFRSF13B基因编码的一种受体,属于肿瘤坏死因子受体超家族(TNF receptor superfamily)。主要存在于B细胞和浆细胞上,并在免疫系统的调控中发挥重要作用。


TACI胞外包含两个半胱氨酸富集结构域(CRD),这两个结构域负责与其主要配体BAFF(B-cell Activating Factor)和APRIL(A Proliferation-Inducing Ligand)结合,使得TACI能够特异性识别和结合配体,从而启动信号传导。TACI信号传导在B细胞的存活、成熟和抗体生成中起关键作用。


吉满生物H_TACI Reporter Cell Line是一种Luciferase报告基因细胞系。当BAFF结合TACI受体后,激活下游信号通路,从而激活荧光素酶(Luciferase)的表达。Luciferase读值即代表信号通路的激活效果,因此可用于TACI相关药物的体外效果评价。


数据展示
相关产品
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