当前位置:产品中心 > 细胞系 > 细胞因子 > IL-4 > IL-4 Reporter Cell Line
IL-4 Reporter Cell Line
基本信息

产品编号:GM-C26301

产品名称:IL-4 Reporter Cell Line

目录价:询价

细胞培养、冻存、复苏试剂准备

生长培养基:F12K+10% FBS+1% P.S+4 μg/mL Blasticidin+200 μg/mL G418+4 μg/mL Puromycin+50 μg/mL Zeocin

细胞冻存液:90% FBS+10% DMSO

Assay Buffer:F12K+10% FBS+1% P.S


简介

白介素-4(IL-4)是一种细胞因子,对Th0分化为Th2细胞至关重要,后者具有抗炎特性。此外IL-4主要Th2细胞分泌,因此形成了Th2细胞环路。IL-4的其他重要功能包括促进B细胞的增殖和分化,以及诱导免疫球蛋白E抗体的合成, 因此该抗体在过敏反应中起到重要作用。此外,IL-4诱导巨噬细胞极化为抗炎M2表型,这有助于减少病理性炎症的发生。信号主要通过IL-4与IL-4Rα和γc结合,激活下游信号通路。


吉满生物IL-4 Reporter Cell Line报告基因细胞系,此细胞不表达人IL-13RA1和IL-13RA2受体,因此可特异性识别人IL-4而不识别人IL-13。当人IL-4与受体结合后激活下游信号通路,从而激活荧光素酶(Luciferase)的表达。该细胞可用于IL-4相关药物的体外效果评价。


数据展示
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Biotinylated Cynomolgus OX40L Protein; His-Avi TagBiotinylated Human OX40L Protein; His-Avi TagCynomolgus OX40 Protein; His Tag
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当前位置:产品中心 > 细胞系 > 细胞因子 > IL-4 > IL-4 Reporter Cell Line

IL-4 Reporter Cell Line
基本信息

产品编号:GM-C26301

产品名称:IL-4 Reporter Cell Line

目录价:询价

细胞培养、冻存、复苏试剂准备

生长培养基:F12K+10% FBS+1% P.S+4 μg/mL Blasticidin+200 μg/mL G418+4 μg/mL Puromycin+50 μg/mL Zeocin

细胞冻存液:90% FBS+10% DMSO

Assay Buffer:F12K+10% FBS+1% P.S


简介

白介素-4(IL-4)是一种细胞因子,对Th0分化为Th2细胞至关重要,后者具有抗炎特性。此外IL-4主要Th2细胞分泌,因此形成了Th2细胞环路。IL-4的其他重要功能包括促进B细胞的增殖和分化,以及诱导免疫球蛋白E抗体的合成, 因此该抗体在过敏反应中起到重要作用。此外,IL-4诱导巨噬细胞极化为抗炎M2表型,这有助于减少病理性炎症的发生。信号主要通过IL-4与IL-4Rα和γc结合,激活下游信号通路。


吉满生物IL-4 Reporter Cell Line报告基因细胞系,此细胞不表达人IL-13RA1和IL-13RA2受体,因此可特异性识别人IL-4而不识别人IL-13。当人IL-4与受体结合后激活下游信号通路,从而激活荧光素酶(Luciferase)的表达。该细胞可用于IL-4相关药物的体外效果评价。


数据展示
相关产品
OX40
H_OX40 Reporter Cell LineH_OX40 Reporter DDX35TM Cell LineCynomolgus_OX40L CHO-K1 Cell Line
H_OX40 CHO-K1 Cell LineH_OX40L CHO-K1 Cell LineH_OX40L HEK-293 Cell Line
Anti-H_OX40 hIgG2 Antibody(Ivuxolimab)Anti-OX40L hIgG1 Reference Antibody(Oxebio)Anti-OX40L hIgG4 Antibody(Amlitelimab)
Anti-OX40L hIgG4 Reference Antibody(Amlbio)

Biotinylated Cynomolgus OX40L Protein; His-Avi TagBiotinylated Human OX40L Protein; His-Avi TagCynomolgus OX40 Protein; His Tag
Cynomolgus OX40L Protein; His TagCynomolgus OX40L Protein; mFc TagHuman OX40 Protein; His Tag
Human OX40L Protein; His TagHuman OX40L Protein; mFc Tag
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