当前位置:产品中心 > 抗体 > Biosimilar抗体 > 细胞因子 > Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)
Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)
基本信息

产品编号:GM-46333AB

产品名称:Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)

目录价:询价


产品配图.jpg


规格货号

GM-46333AB-10           10 μg

GM-46333AB-100         100 μg

GM-46333AB-1000       1mg



产品简介

Species Reactivity      Human

Clone                           Ustekinumab

Source/Isotype           Monoclonal Human IgG1/κ

Application                 Block assay

Specificity                   Detects IL-12/23

Gene                            IL-12/23

Background                Interleukin-12 (IL-12) is a receptor for IL-12R and belongs to the type I cytokine receptor family. This cytokine acts as a growth factor for activated T cells and natural killer cells, enhances the lytic activity of natural killer cells or lymphokine-activated killer cells, and stimulates IFN-γ production through resting PBMC. Il-23 encodes a subunit of the heterodimer cell factor interleukin 23(IL 23),The gene consists of its protein and the p40 subunit of interleukin 12(IL12B). The receptor for IL23 consists of the β1 subunit of IL12 (IL12RB1) and the specific subunit of IL23, IL23R. Both IL 23 and IL 12 activate the transcriptional activator STAT4 and stimulate the production of interferon gamma (IFNG). Compared with IL 12, which mainly acts on infantile CD4(+)T cells, IL 23 preferentially acts on memory CD4(+)T cells. Anti-IL-12/23(Ustekinumab) hIgG1 antibody is a human immunoglobulin (Ig) G1 kappa monoclonal antibody that targets interleukin (IL-12) and IL-23. It is used to treat various inflammatory conditions involving activation of the IL-12 and IL-23 signaling pathways.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay



数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)

Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)
基本信息

产品编号:GM-46333AB

产品名称:Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)

目录价:询价


产品配图.jpg


规格货号

GM-46333AB-10           10 μg

GM-46333AB-100         100 μg

GM-46333AB-1000       1mg



产品简介

Species Reactivity      Human

Clone                           Ustekinumab

Source/Isotype           Monoclonal Human IgG1/κ

Application                 Block assay

Specificity                   Detects IL-12/23

Gene                            IL-12/23

Background                Interleukin-12 (IL-12) is a receptor for IL-12R and belongs to the type I cytokine receptor family. This cytokine acts as a growth factor for activated T cells and natural killer cells, enhances the lytic activity of natural killer cells or lymphokine-activated killer cells, and stimulates IFN-γ production through resting PBMC. Il-23 encodes a subunit of the heterodimer cell factor interleukin 23(IL 23),The gene consists of its protein and the p40 subunit of interleukin 12(IL12B). The receptor for IL23 consists of the β1 subunit of IL12 (IL12RB1) and the specific subunit of IL23, IL23R. Both IL 23 and IL 12 activate the transcriptional activator STAT4 and stimulate the production of interferon gamma (IFNG). Compared with IL 12, which mainly acts on infantile CD4(+)T cells, IL 23 preferentially acts on memory CD4(+)T cells. Anti-IL-12/23(Ustekinumab) hIgG1 antibody is a human immunoglobulin (Ig) G1 kappa monoclonal antibody that targets interleukin (IL-12) and IL-23. It is used to treat various inflammatory conditions involving activation of the IL-12 and IL-23 signaling pathways.

Storage                        Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.

Formulation                Phosphate-buffered solution, pH 7.2.

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay



数据展示

image.png

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