当前位置:产品中心 > 抗体 > Biosimilar抗体 > 抗体功能 > Anti-FcRn hIgG4 Reference Antibody(Rozabio)
Anti-FcRn hIgG4 Reference Antibody(Rozabio)
基本信息

产品编号:GM-87351MAB

产品名称:Anti-FcRn hIgG4 Reference Antibody(Rozabio)

目录价:询价


产品配图.jpg


规格货号

GM-87351MAB-1mg / 1 mg

GM-87351MAB-5mg / 5 mg

GM-87351MAB-25mg / 25 mg

GM-87351MAB-50mg / 50mg

GM-87351MAB-100mg / 100 mg



产品简介

Expression System     CHO

Aggregation               < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                   < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          FcRn

Clone                             Rozanolixizumab

Alternative Names       FCGRT, FcgammaRn, alpha-chain

Source/Isotype           Human IgG4(S228P), Kappa

Application                 /

Description                   The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the FCGRT gene. It is an IgG Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. In rodents, FcRn was originally identified as the receptor that transports maternal immunoglobulin G (IgG) from mother to neonatal offspring via mother's milk, leading to its name as the neonatal Fc receptor. In humans, FcRn is present in the placenta where it transports mother's IgG to the growing fetus. FcRn has also been shown to play a role in regulating IgG and serum albumin turnover. Neonatal Fc receptor expression is up-regulated by the proinflammatory cytokine, TNF-α, and down-regulated by IFN-γ.

Formulation               Phosphate-buffered solution, pH 7.4.


数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-FcRn hIgG4 Reference Antibody(Rozabio)

Anti-FcRn hIgG4 Reference Antibody(Rozabio)
基本信息

产品编号:GM-87351MAB

产品名称:Anti-FcRn hIgG4 Reference Antibody(Rozabio)

目录价:询价


产品配图.jpg


规格货号

GM-87351MAB-1mg / 1 mg

GM-87351MAB-5mg / 5 mg

GM-87351MAB-25mg / 25 mg

GM-87351MAB-50mg / 50mg

GM-87351MAB-100mg / 100 mg



产品简介

Expression System     CHO

Aggregation               < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                   < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          FcRn

Clone                             Rozanolixizumab

Alternative Names       FCGRT, FcgammaRn, alpha-chain

Source/Isotype           Human IgG4(S228P), Kappa

Application                 /

Description                   The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the FCGRT gene. It is an IgG Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. In rodents, FcRn was originally identified as the receptor that transports maternal immunoglobulin G (IgG) from mother to neonatal offspring via mother's milk, leading to its name as the neonatal Fc receptor. In humans, FcRn is present in the placenta where it transports mother's IgG to the growing fetus. FcRn has also been shown to play a role in regulating IgG and serum albumin turnover. Neonatal Fc receptor expression is up-regulated by the proinflammatory cytokine, TNF-α, and down-regulated by IFN-γ.

Formulation               Phosphate-buffered solution, pH 7.4.


数据展示

image.png

image.png

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