当前位置:产品中心 > 抗体 > Biosimilar抗体 > 免疫 > Anti-TL1A hIgG1 Reference Antibody (Duvbio)
Anti-TL1A hIgG1 Reference Antibody (Duvbio)
基本信息

产品编号:GM-87806MAB

产品名称:Anti-TL1A hIgG1 Reference Antibody (Duvbio)

目录价:询价


产品配图.jpg


规格货号

GM-87806MAB-1mg / 1 mg

GM-87806MAB-5mg / 5 mg

GM-87806MAB-25mg / 25 mg

GM-87806MAB-50mg / 50 mg

GM-87806MAB-100mg / 100mg



产品简介

Expression System      CHO

Aggregation                < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          TL1A

Clone                           Duvakitug 

Alternative Names     TL1; TL1A; VEGI; TNLG1B; VEGI192A

Source/Isotype           Human IgG1(KDEL), Lamda2

Application                 /

Description                 The protein encoded by TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells but is not expressed in either B or T cells. The expression of this protein is inducible by TNF-alpha and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 (death receptor 3) and TNFRSF6B (decoy receptor 3). It can activate both the NF-κB and MAPK signalling pathways and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined.

Formulation                phosphate-buffered solution, pH 7.4.



数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-TL1A hIgG1 Reference Antibody (Duvbio)

Anti-TL1A hIgG1 Reference Antibody (Duvbio)
基本信息

产品编号:GM-87806MAB

产品名称:Anti-TL1A hIgG1 Reference Antibody (Duvbio)

目录价:询价


产品配图.jpg


规格货号

GM-87806MAB-1mg / 1 mg

GM-87806MAB-5mg / 5 mg

GM-87806MAB-25mg / 25 mg

GM-87806MAB-50mg / 50 mg

GM-87806MAB-100mg / 100mg



产品简介

Expression System      CHO

Aggregation                < 5% as determined by SEC-HPLC

Purity                           > 95% as determined by SDS-PAGE

Endotoxin                    < 1 EU/mg, determined by LAL gel clotting assay

Sterility                        0.2 μm Filtered

Target                          TL1A

Clone                           Duvakitug 

Alternative Names     TL1; TL1A; VEGI; TNLG1B; VEGI192A

Source/Isotype           Human IgG1(KDEL), Lamda2

Application                 /

Description                 The protein encoded by TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells but is not expressed in either B or T cells. The expression of this protein is inducible by TNF-alpha and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 (death receptor 3) and TNFRSF6B (decoy receptor 3). It can activate both the NF-κB and MAPK signalling pathways and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined.

Formulation                phosphate-buffered solution, pH 7.4.



数据展示

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