产品编号：GM-88265AB
产品名称：Anti-IL1B×IL1A hIgG1 Bispecific Antibody(lutikizumab)
目录价：询价
产品编号：GM-88265AB
产品名称：Anti-IL1B×IL1A hIgG1 Bispecific Antibody(lutikizumab)
目录价：询价
GM-88265AB-10 10 μg
GM-88265AB-100 100 μg
GM-88265AB-1000 1mg
Species Reactivity | Human |
Clone | lutikizumab |
Source/Isotype | Human IgG1(L234A,L235A,D356E,L358M), kappa |
Application | Bioactivity-ELISA |
Target | Detects IL1B / IL1A |
Gene | IL1B; IL1A |
Other Names | IL1B: IL-1, IL1-BETA, IL1F2, IL1beta IL1A: IL-1 alpha, IL-1A, IL1, IL1-ALPHA, IL1F1 |
Gene ID | IL1B (3553);IL1A (3552) |
Background | IL1A and IL1B belong to the same IL-1 cytokine family and are located adjacent to the Q13 region of human chromosome 2 Lutikizumab is an anti-il-1α and il-1β bivariate domain immunoglobulin that centrally targets two key proinflammatory cytokines, il-1α and il-1β, and has been shown to inhibit the production of il-1α and il-1β, a series of clinical studies have been carried out in the field of osteoarthritis (especially synovitis subtypes) by blocking IL-1 pathway-mediated inflammatory response through precise dual-target recognition and inhibition mechanisms, it provides a new direction for the treatment exploration of inflammatory phenotype osteoarthritis. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
产品编号：GM-88265AB
产品名称：Anti-IL1B×IL1A hIgG1 Bispecific Antibody(lutikizumab)
目录价：询价
GM-88265AB-10 10 μg
GM-88265AB-100 100 μg
GM-88265AB-1000 1mg
Species Reactivity | Human |
Clone | lutikizumab |
Source/Isotype | Human IgG1(L234A,L235A,D356E,L358M), kappa |
Application | Bioactivity-ELISA |
Target | Detects IL1B / IL1A |
Gene | IL1B; IL1A |
Other Names | IL1B: IL-1, IL1-BETA, IL1F2, IL1beta IL1A: IL-1 alpha, IL-1A, IL1, IL1-ALPHA, IL1F1 |
Gene ID | IL1B (3553);IL1A (3552) |
Background | IL1A and IL1B belong to the same IL-1 cytokine family and are located adjacent to the Q13 region of human chromosome 2 Lutikizumab is an anti-il-1α and il-1β bivariate domain immunoglobulin that centrally targets two key proinflammatory cytokines, il-1α and il-1β, and has been shown to inhibit the production of il-1α and il-1β, a series of clinical studies have been carried out in the field of osteoarthritis (especially synovitis subtypes) by blocking IL-1 pathway-mediated inflammatory response through precise dual-target recognition and inhibition mechanisms, it provides a new direction for the treatment exploration of inflammatory phenotype osteoarthritis. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
