产品编号:GM-C05346
产品名称:TGF-β Reporter HEK-293 cell line
目录价:询价
产品编号:GM-C05346
产品名称:TGF-β Reporter HEK-293 cell line
目录价:询价
生长培养基: DMEM + 10% FBS+4 μg/mL Blasticidin +125 μg/mL Hygromycin+ 0.75 μg/mL Puromycin +400 μg/mL G418+1%P.S
细胞冻存液: 90% FBS+10% DMSO
Assay Buffer: DMEM +1% FBS +1% P.S
TGF-β超家族是一个成员众多的细胞因子家族,包括TGF-β、Activin、Nodal、骨形成蛋白(BMP)、生长与分化因子(GDF)等。TGF-β受体能够激活smad依赖型的信号通路和非smad依赖型的信号通路,参与调控细胞增殖、分化、衰老、死亡、胞外基质重塑、迁移,以及细胞命运决定等生理过程,并在早期胚胎发育、组织器官形成,和成体组织稳态中发挥重要作用。
吉满生物TGF-β Reporter HEK-293 Cell Line报告基因细胞系稳定表达TGF-β通路相关报告基因及TGF-β的受体,可用于TGF-β通路相关小分子药物或单抗、双抗的研究。
Qian X, Li H, Teng F, et al. Bi-functional molecules: U.S. Patent Application 18/253,398[P]. 2024-2-8.
Li TT, Su XW, Chen LL, Zhang WN, Zhang JP, Wang Y, Xu WH. Roxarsone inhibits hepatic stellate cell activation and ameliorates liver fibrosis by blocking TGF-β1/Smad signaling pathway. Int Immunopharmacol. 2023 Jan;114:109527. Epub 2022 Dec 19. PMID: 36700762.
Wu ZH, Li N, Gao ZZ, Chen G, Nie L, Zhou YQ, Jiang MZ, Chen Y, Chen J, Mei XF, Hu F, Wang HB. Development of the Novel Bifunctional Fusion Protein BR102 That Simultaneously Targets PD-L1 and TGF-β for Anticancer Immunotherapy. Cancers (Basel). 2022 Oct 10;14(19):4964. PMID: 36230887.
Rui Y, Han X, Jiang A, Hu J, Li M, Liu B, Qian F, Huang L. Eucalyptol prevents bleomycin-induced pulmonary fibrosis and M2 macrophage polarization. Eur J Pharmacol. 2022 Sep 15;931:175184. Epub 2022 Aug 12. PMID: 35964659.
产品编号:GM-C05346
产品名称:TGF-β Reporter HEK-293 cell line
目录价:询价
生长培养基: DMEM + 10% FBS+4 μg/mL Blasticidin +125 μg/mL Hygromycin+ 0.75 μg/mL Puromycin +400 μg/mL G418+1%P.S
细胞冻存液: 90% FBS+10% DMSO
Assay Buffer: DMEM +1% FBS +1% P.S
TGF-β超家族是一个成员众多的细胞因子家族,包括TGF-β、Activin、Nodal、骨形成蛋白(BMP)、生长与分化因子(GDF)等。TGF-β受体能够激活smad依赖型的信号通路和非smad依赖型的信号通路,参与调控细胞增殖、分化、衰老、死亡、胞外基质重塑、迁移,以及细胞命运决定等生理过程,并在早期胚胎发育、组织器官形成,和成体组织稳态中发挥重要作用。
吉满生物TGF-β Reporter HEK-293 Cell Line报告基因细胞系稳定表达TGF-β通路相关报告基因及TGF-β的受体,可用于TGF-β通路相关小分子药物或单抗、双抗的研究。
Qian X, Li H, Teng F, et al. Bi-functional molecules: U.S. Patent Application 18/253,398[P]. 2024-2-8.
Li TT, Su XW, Chen LL, Zhang WN, Zhang JP, Wang Y, Xu WH. Roxarsone inhibits hepatic stellate cell activation and ameliorates liver fibrosis by blocking TGF-β1/Smad signaling pathway. Int Immunopharmacol. 2023 Jan;114:109527. Epub 2022 Dec 19. PMID: 36700762.
Wu ZH, Li N, Gao ZZ, Chen G, Nie L, Zhou YQ, Jiang MZ, Chen Y, Chen J, Mei XF, Hu F, Wang HB. Development of the Novel Bifunctional Fusion Protein BR102 That Simultaneously Targets PD-L1 and TGF-β for Anticancer Immunotherapy. Cancers (Basel). 2022 Oct 10;14(19):4964. PMID: 36230887.
Rui Y, Han X, Jiang A, Hu J, Li M, Liu B, Qian F, Huang L. Eucalyptol prevents bleomycin-induced pulmonary fibrosis and M2 macrophage polarization. Eur J Pharmacol. 2022 Sep 15;931:175184. Epub 2022 Aug 12. PMID: 35964659.